Dajirali: Bridging Surface Modification ani sɛgɛsɛgɛli tigitigi
Ɲɛnamaya dɔnniyaw ni sɛgɛsɛgɛliw cogoya min bɛ ka wuli, minɛn kɛrɛnkɛrɛnnenw donli baarakɛcogo la, o ye ko bɛɛ la belebele ye walasa ka ɲininiw lasegincogo sabati ani ka sɔrɔli teliya. Laboratowari korona furakɛlikɛlan, n’o ye minɛn ye min dilannen don walasa ka dugukolo sanfɛla baara tigitigi kuran bɔli fɛ, o ni fɛnw dɔnniya ni izini taabolo bɛ tali kɛ ɲɔgɔn na laada la. Nka, a seko bɛ bi, kunnafonidilanw-labɔra laboratuwari sigidaw kɔnɔ-kɛrɛnkɛrɛnnenya la, n’a bɛ tali kɛ fɛnɲɛnamaw ni selilɛriw ka sɛgɛsɛgɛli ɲɛtaalenw na-o tora dancɛ ye min bɛ mɔgɔ bila ka fɛn kuraw don.
Koronawirisi furakɛli jɔyɔrɔ ka ɲɛsin sɛgɛsɛgɛli jɔnjɔnw labɛnni ma
A kɔnɔna na, laboratuwari koronawirisi furakɛlikɛla bɛ dugukolo sanfɛla fanga sɛmɛntiya ni tension caman bɔli ye fɛn dɔ kan, o kɛcogo min bɛ jate ni paramɛtɛrɛw ye i n’a fɔ fanga (W) min ye furakɛli hakɛ, teliya, bonya, ani masin paramɛtiriw baara ye. Nin sanfɛla baarakɛcogo kɔrɔsilen in ye labɛnko ye min nafa ka bon kosɛbɛ, nka a ka c’a la, a bɛ ye ka ban, biyoanalitiki baarakɛcogo caman na. Misali la, banakisɛ walima hadamadenw ka seliluw sɛnɛni n’u sɛgɛsɛgɛli la, substrat jisigicogo ni u nɔrɔli basigilen tɛ -negosiable ye walasa ka sɛgɛsɛgɛli dannaya kɛ. A kɛra polimɛri sanfɛyɔrɔw labɛnni ye minɛn fitininw dilanni kama walasa ka banakisɛw don nanolitiri jikuruw kɔnɔ, walima ka sɛnɛfɛnw furakɛ walasa ka hadamadenw ka sugunɛbilenni banakisɛw nɔrɔ ka ɲɛ biyomimɛtiki jeliw kɔnɔ, koronawirisi furakɛli bɛ daminɛ cogoya kelenw sabati. Nin sariyasun in min bɛ kɛ misali labɛnni yɔrɔ la, o bɛ dɔ fara duguma, sɛgɛsɛgɛliw kan minnu bɛ se ka kɛ kosɛbɛ, olu ka kantigiya kan k’a ɲɛsin u yɛrɛ ma.
Jɛɲɔgɔnya ni sɛgɛsɛgɛli ni kɔlɔsili baarakɛcogo kɔrɔlenw ye
Laboratowari koronawirisi furakɛli nafa lakika bɛ dabɔ a ka donbaliya fɛ laboratuwari sigida laminiw na minnu ka bon, minnu sirilen don ɲɔgɔn na. Aw bɛ baarakɛcogo dɔ jateminɛ banakisɛfagalanw tali sɛgɛsɛgɛli kama. Taabolo bɛ se ka daminɛ ni korona-furakɛli yɔrɔw ye minnu bɛ jikuruw dilancogo ɲuman sabati banakisɛw ka selilu kelen-kɔnɔna na. Kɔnɔnatumu kɔfɛ, sɛgɛsɛgɛli teliyalenw bɛ kɛ, i n’a fɔ latex agglutination walasa ka Streptococcus pneumoniae dɔn walima ka Methicillin-Resistant Staphylococcus aureus (MRSA) sɔrɔ. Fɛnɲɛnɛma furakɛli fɔlɔ bɛ kɛ sababu ye ka nin fɛn teliyalenw baara cogo basigilen na, n’a y’a to reagents bɛ ɲɔgɔn sɔrɔ cogo kelen na ni kɔlɔn plati furakɛlenw ye walima ni slide surfaces ye. Ka fara o kan, selilɛri-sɛgɛsɛgɛliw la i n’a fɔ fura jɛnsɛnni hakɛ jateminɛni-yɔrɔ minnu na seliluw bɛ mara kunnafonidilanw kɔnɔ minnu faralen don den kɔnɔ misiw ka jolisegindumuniw kan ani banakisɛfagalanw-korona-furalenw sɛnɛminɛnw kɔnɔ, olu bɛ selilu kelen-kelenw sabati, o bɛ na ni ja ni kunnafoniw hakɛ jateminɛni ye minnu bɛ se ka segin ka kɛ ɲɔgɔn fɛ. O bɛ cakɛda jɛlen dɔ Dabɔ k’a Tà misali labɛnni na ka Taa Se sɛgɛsɛgɛli ma, ka fɛn caman Dɔgɔya minnu bɛ Dòn substrat (substrate) bɛnbaliya fɛ.
Nizɛri jiginni ɲɛminɛni ani hadamaden ka ko kɛlenw ɲɛnabɔli
Minɛnw farali ɲɔgɔn kan i n’a fɔ korona furakɛlikɛla, o tɛ tɛmɛ farikolo baarakɛcogo bilali dɔrɔn kan; o ye laboratuwari nizɛri jiginni yɔrɔ koloma ye. Bi laboratuwari in laɲini ye ka baarakɛcogo bɛɛ siri ɲɔgɔn na, k’a ta minɛnw ni fɛnw na minnu bɛ se ka kɛ, ka se baarakɛcogo ni kunnafonidilanw ma. Korona furakɛlikɛla hakilitigi, min ni ɲɔgɔn cɛsirilen don, o bɛ se ka furakɛli paramɛtiriw (misali la, Se (W), a jirali waati) sɛbɛn ka ɲɛsin laboratuwari kaye nimɔrɔma ma walima Laboratoire Information Management System (LIMS) kɔnɔ. O bɛ sira dɔ labɛn min bɛ se ka jateminɛ kɛ labɛncogo kɔrɔw kama, ka sariya labatoli n’a lasegincogo sabati. Ni nin kunnafoniw farala ɲɔgɔn kan ni sɔrɔw ye minnu bɔra senfɛwale nataw la-i n’a fɔ banakisɛw ka bonya jateminɛw ka bɔ jikuruw kɔlɔsili la walima selilɛriw tali kunnafoniw ka bɔ ja lajɛw la-dɔnniyakɛlaw bɛ se ka hakilina juguw sɔrɔ sɛgɛsɛgɛli ɲɛtaa fɛ. O jɛɲɔgɔnya in bɛ dɔ bɔ bololabaarakɛlaw ka sɛbɛnni filiw la, ka minɛnw jɔli waati la, ani ka laboratuwari fɛnw baaracogo ɲuman kɛ. A laban na, ni sanfɛla labɛnni taabolo kɛra otomatiki ye ani k’a sɛbɛn, o fɛɛrɛ in bɛ dɔ bɔ bololabaara sɛgɛnbaliw la, o b’a to dɔnnikɛlaw bɛ se k’u sinsin nafa caman sɛgɛsɛgɛli ni latigɛw kan minnu ka bon-. O bɛ bɛn laɲini ma, n’o ye ka hadamadenw ka ko kɛlenw ɲɛnabɔ ka ɲɛ laboratuwari kɔnɔ, ka baarakɛcogo ɲɛ, ka da u kan, ani ka hakili ta fan fɛ.
Kuncɛli ani siniko jateminɛw
Laboratowari korona furakɛlikɛlan donli sɛgɛsɛgɛli baarakɛcogo caman na, o bɛ kɛ sababu ye ka ɛntɛrinɛti injiniyɛri tigitigi, mikrobiologi, ani laboratuwari nizɛri ɲɛnabɔli ka ɲɔgɔn sɔrɔ. Ni fɛɛrɛ barikama dilen don walasa ka dugukolo sanfɛla cogoyaw sigi senkan, a bɛ tigɛda{1}}fɛɛrɛw dannaya sinsin, k’a ta selilu kelen-banakisɛw sɛgɛsɛgɛli la ka se 3D selilɛriw sɛnɛcogo misali gɛlɛnw ma. Ni laboratuwaraw bɛ ka taa a fɛ ka wuli ka kɛ sigida hakilitigiw ye, minnu ni ɲɔgɔn cɛsirilen don, o fɛɛrɛ jɔnjɔn suguw jɔyɔrɔ bɛna bonya dɔrɔn. Yɛlɛma nataw bɛ se ka kɛ sababu ye ka korona furakɛlikɛlaw ye ni sensɛriw ye minnu jɔlen don-u kɔnɔ walasa ka waati yɛrɛyɛrɛ-yɔrɔ sanfɛla fanga sɛgɛsɛgɛli kɛ, walima hali ka jɛɲɔgɔnya gɛlɛn don ni ji minɛcogo otomatiki ye, ka ɲɔgɔndan datugu ka taa a fɛ misali labɛnni, sɛgɛsɛgɛli, ani kunnafonidilanw-sɔrɔli siratigɛ la. Nin jɛ-ka-baara in minɛni tɛ fɛɛrɛko yiriwali dɔrɔn ye, nka a ye fɛɛrɛ tigɛlen ye walasa ka dɔnniya baarakɛyɔrɔw jɔ minnu bɛ se ka muɲu, minnu bɛ nafa sɔrɔ, ani minnu bɛ fɛn kuraw bɔ.